Things I’ve looked up recently

Kienböck Disease

Feasibility of high intensity training in asthma

High intensity interval training increases the clinical control, aerobic fitness and decreases dyspnea in severe asthmatics

What is spinning

Vascularized medial femoral trochlea osteochondral flap reconstruction of advanced Kienböck disease

The Year of Mind, Body, and… Wallet

Without really meaning to, I’ve decided to try to make this a year (or more) of mind, body, and wallet. Meaning that during the same time frame I’ve somehow decided to 1) focus more fully on fitness, 2) read at least 10-20 books of “literature” for 2022, and 3) limit my spending.

The fitness backstory: 2021 was a year of surprise medical problems. From the months of March to May in 2021, during what I felt was a giant positive upswing in my fitness journey (I was looking fit, toned, and strong; I was using my Olympic weight set), I started bleeding. Like, a lot. I was hemorrhaging. I had to go to the Emergency Room twice because the first time, I’d lost a quarter of my blood volume and the second time, I was well on my way to losing half my blood. Both ended up in hospital stays. I got put on different medicines to try to stop the bleeding. They never worked completely. In May, I underwent a hysterectomy and everything that was wrong in that part of my body was taken out. And after I healed (3 whole months for full healing), I had to deal with weakened muscles that ended up in back pain for which I went to physical therapy. After a few more months, I finally felt ready to start my fitness journey over. But during these months, I had gotten out of shape and weak. I wanted to be strong again. I really started rock climbing regularly and did some light weights to start, but it was in December that I felt strong enough to really take my 20- and 30-pound dumbbells seriously. So for 2022 I decided to finish what I’d started 1.5 years ago.

Reading: 2021 was also a year of loss. Like I mentioned before, I inherited a few old books from someone who was gone too soon due to Covid and never visiting the doctor, like, ever. Reading Ulysses (I’m now halfway through it) has ignited within me a desire to read more literary fodder, as in anything that’s not a “quick airport book from a tiny newsstand.” The types of books that you don’t have to think about. I do enjoy the relaxed non-heavy read. But, it’s not like I’ve never read anything substantial. I went through a beatnik phase and a William Faulkner phase. I had a Tom Robbins phase. I took Philosophy classes in college (which forced me to read Plato, Aristotle, Hume, etc.) and I read stuff like Bertrand Russell for fun. My high school had me read a lot of classics because it was 3 years of Honors English and 1 of AP English. But there were still books that were out of my reach or kind of slippery because I was simply too ADD to focus on them. But now I’m 2 decades older, my ADD is controlled, and I have the time and the life knowledge to tackle books I’ve missed. Which books? Well, I’m not sure yet. There are lists of books all over the place. My first thought is to balance the reading so that I’m not reading War and Peace and Anna Karenina at the same time, that there is a difference in time, place, author, and culture. I’d also like to read across genres and points of view. Variety is the spice of life, they say.

So far this year I’ve finished Circe by Madeline Miller and Klara and the Sun by Kazuo Ishiguro. (One of those was deeper than the other.) I’ve got Invisible Cities by Italo Calvino*, All Systems Red by Martha Wells*, Dune, and Rebecca by Daphne du Maurier* on rotation. And of course, Ulysses. From the library I have one Neal Stephenson book, Fall, or Dodge in Hell. On my “next” list is A Portrait of the Artist as a Young Man, The Three Body Problem by Cixin Liu*, and Tropic of Cancer by Henry Miller. On my bookshelf are Infinite Jest by David Foster Wallace, Gravity’s Rainbow by Thomas Pynchon, and the writings of H. P. Lovecraft. There are even more books in my Kindle and on my ebook “to read” list. My intention is to pick books that can make me pause and think, but sometimes, I’m not sure every book I pick will do that. Circe was a lot simpler read than I had thought; it was good but not as dense as I thought it would be. (I’d recommend Galatea by Madeline Miller as a more thoughtful read). In any case, I’m sure I’ll write about the things I read.

The wallet: Suddenly one day I pondered if I could do an entire year of “no spending”. This was after the splurging I did in November and December to set up my workstation at home with 2 4k monitors and a docking station. I also bought a bookshelf. Not to mention everyone’s holiday gifts. Then one day after Christmas, it hit me that I could try to do a “no spend” month where I didn’t buy anything on impulse or that I didn’t really need. I wondered how much money I could save. I thought about what were “approved” spends and “bad” spends — and if you’ve never thought of this before, it is an enlightening exercise. For people doing this, the first thing they must do is to make lists of what’s a “need” versus a “want”, what’s okay to spend on, and what isn’t. (One can look up “no spend year” and find a million links and social media about the topic.) I read this Forbes article to start.

What’s nice about the No Spending thing is that it’s personalized, for the most part. I, for instance, do not need the latest game console or video game, because nothing I do depends on that. Someone else might. Someone else might not need shampoo and conditioner, but I do, or else my hair turns into a giant, out-of-control tumbleweed. I can broadly put down in the “approved” list things like medical bills, medicines, things for health maintenance, insurance, and things for health improvements. Other “approved” spending includes food (nothing carb-loaded or deep fried), gifts (dollar limits depending on what the gift is for), car maintenance, house maintenance, vacation, and replacements for things I already own if they are used up or worn down, like soap. It’s easy to write “No late-night Amazon browsing” and remember it, hence, cutting out the possibility of ordering something half-asleep. Also, it’s easy to remember “no more clothes” and “no impulse buying”. This past week, this “resolution” has reared up at Target, Best Buy, and the grocery store, successfully convincing me to not buy something just for the sake of buying it. It was both difficult and empowering. Once January is over, I’ll try February. I’m hoping that eventually, this will turn into a habit and my wallet will be happier for it.

*Books that are ebook or library loans will have priority.

Mitochondrial diseases

Sometimes I work on a case with a rare disease. In one year, I probably come across 5-8 rare diseases, which of course I have to look up because, well, what the hell is this?

One kind of disease that scare me are mitochondrial diseases. These are a group of conditions that are caused by genetic mutations in the mitochondrial DNA that make the mitochondria work abnormally. And if you remember anything about high school biology, mitochondrial are the “powerhouses” of the cell — they produce energy for us to use. So one can imagine that if you have something wrong with your power source, you can’t carry out normal functioning. Also, mitochondrial DNA are only carried in the egg cells, so only mothers can pass this down to their children. Sperm cells don’t carry and therefore don’t contribute mitochondria to the next generation.

It’s crazy how such a small thing can generally f*&k up a life. The US Health & Human Services National Institutes of Health website lists common signs and symptoms such as: poor growth, loss of muscle coordination, muscle weakness, seizures, autism, problems with vision and/or hearing, developmental delay, heart/liver/kidney disease, gastrointestinal disorders, dementia, to name some. You can see what mitochondrial diseases affect in this list of free text research articles at PubMed (I don’t have any institutional access, so I look for free text articles). Then I thought about prenatal testing, and found an article that discusses this, a more recent 2021 article of a study in Japan, and recent (as of 2017) advances in mitochondrial diseases. This article from 2020 is about rare genetic diseases in general, and diagnosing them. If there’s anything I’ve learned from skimming through these articles, it’s that there’s still so much we don’t know. Yet.

Ulysses: Page 249

At this moment, I’m on page 249 of Ulysses. The first two “chapters” were fine, but quickly ramped up from here such that I’m swallowed up by references, themes, mythology, languages, and details. Any chapter from the viewpoint of Stephen Daedalus is really hard to get through, so it take me a long while to finish those parts. There are Post-Its all over the place with words I don’t know, and I’m underlining phrases I find interesting, deep, funny, or incomprehensible. All of which have caused me to look up online resources in order to more fully understand and appreciate what I’m reading:

Michael Groden’s Notes of Ulysses

I’m currently watching the Hades episode in this series of YouTube videos: Reading Ulysses for Fun. There is a video for each “chapter”, plus additional videos. This series is super helpful in explaining and pointing the way.

Gilbert Schema for Ulysses

Guide to Ulysses (includes a guide for each episode)

The Joyce Project – where you can read the book where parts of it are annotated. I bought an annotated version for my Kindle so I’m using that when I don’t want to lug my book around (my book is hardcover, the “completed and unabridged text, as corrected and entirely reset in 1961”, and contains the new forward by the author and “the historic decision by Judge John M. Woolsey whereby the Federal ban on Ulysses was finally removed”. I can’t find a picture of the exact edition online; the ones that look like the cover I have are labeled “paperback”, but I have the hardcover).

OMG, Omicron

Research is what I’m doing when I don’t know what I’m doing.

Wernher von Braun

For the past year and a half, if anyone wanted, they could look to see how science is being done just by looking up research on the SARS-CoV-2 virus. If pandemics were a reality show… Now season 3 is upon us, cursing us with another variant. Like the beginning of finding out about the SARS-CoV-2 virus and finding out about the Delta variant, science is trying to figure this one out. I know that it’s frustrating that no one knows the answer right away, but one thing people miss about science is that it isn’t about knowing everything, but it’s about finding things out. And in order to find things out, we need time. However, in a pandemic, time is an enemy. What some people get wrong is that this is confused with “science is the enemy” or “those other people are the enemy” or “this country is the enemy”. Let’s skip the philosophical part and say that basically, we’re afraid of the unknown, especially if the unknown can maim/kill us.

Although science is more about questions than answers, it can and does generate light that we can shine on the unknown. For example, every Mars rover. Because of my science background (where I spent an extremely long time trying to figure out which science field I wanted to be in, while taking every science class there was), I can go through research articles and figure out what’s what. Here’s a controversial idea: every person should take a class on how to look up scholarly articles on any topic in high school. (While we’re here, let’s open up a school and call it “School of Hard Knocks”, in which every class is directly applicable to real life, such as How to Do Your Taxes, or 50 Cheap, Simple, and Healthy Meals). Anyway, for an average person without a science background (which I also once was, in the early 2000s), what sources are there for just plain facts and neutral ground?

So far, here is the general answer:

I’m happy to see that BBC is in the center, because a long time ago, someone told me that if I wanted to find something neutral, a good point of view to consider would be from people outside of the country. I mean, how good are we at being objective about the aquariums we’re swimming in? And I’m also happy to see Reuters next to BBC. What was interesting was that I had thought The Economist was more right leaning than it was. Finally, it’s nice to know others I haven’t thought of, like Associated Press, to add to my bookmarks.

So what about Omicron? Do we need a booster shot for that? How bad is it, compared to what’s happened already? The answer is, We don’t know… yet.

Now, once again, the world is watching as researchers work nights and weekends to learn what a new variant has in store for humanity. Is Omicron more infectious? More deadly? Is it better at reinfecting recovered people? How well does it evade vaccine-induced immunity? And where did it come from? Finding out will take time, warns Jeremy Farrar, head of the Wellcome Trust: “I’m afraid patience is crucial.”

‘Patience is crucial’: Why we won’t know for weeks how dangerous Omicron is

Talking about sources wasn’t random. I liked this article for its readability, its short length, its international tidbits, and that it shares knowledge (PCR, GISAID database, structural biology mapping) without sensationalizing or politicizing anything. In this day and age, it’s like gold.

I didn’t know there was a competition for that

Sometimes I come across a sport/activity that one would never think would be at the level of world championship, or even a regular championship for that matter.

The Slippery Stairs Championship

World Chase Tag – yup, the old schoolyard game has a championship.

National Air Guitar Championship – maybe the least surprising, but I didn’t expect that one could even judge air guitar in order to pick a winner.

Dods Championship – looks like the opposite of Olympic diving.

Ostrich racing. I knew you could ride on them!

And my favorite, the medieval knight fights. There are many videos of this new (old) form of MMA. It looks like no matter how strong/big you are, it’s still going to be an exhausting endeavor.

A False Choice Between Individual Freedom and Public Health

I’ve been thinking about the issue of “Individual Freedom” and “Public Health” lately, in light of dozens of news articles, Facebook rants, face-palm anti-vaxxer deaths, vaccine mandates, and me being a nurse who believes in individual freedom but have a huge science background. Are there any law-based article discussing the intersection of individual freedom and public health?

Well, Google scrounged up this article called “Individual Freedom or Public Health? A False Choice in the Covid Era.” It makes a good point: every argument, decision, rant, etc. has been falsedly based on one (individual freedom) or the other (public health). Our communities, politicians, and talking heads have set up this dichotomy and most of us have fallen head first into it and taken sides. They have set up this dichotomy in that we lose whether we choose one or the other. Instead, they could have set it up so that it’s a win-win situation.

For the real sacrifice involved in social distancing and stay-at-home orders is not individual freedom. It is the reality that these measures can cause more hardship for some people than others. For some, that hardship may be lost income; for others it may be the inability to visit their parents in a long-term care facility; for still others, it may be domestic violence…

…we should be providing people with the economic and social supports they need to maintain physical distancing. The problem is that these supports are the very things that many politicians are loathe to provide…

It is not authoritarian to demand that people maintain physical distance to save lives. It is authoritarian to demand it without giving diverse people the means to do it.

-Jonathan Cohen, “Individual Freedom or Public Health? A False Choice in the Covid Era

It’s Different in Girls

I just navigated to this article by Scientific American. Even though I am not diagnosed as autistic, it still strikes a chord with me, especially these paragraphs:

But inside, it was very different. Social life did not come at all naturally to her. She used her formidable intelligence to become an excellent mimic and actress, and the effort this took often exhausted her. From the time she started reading at three and throughout her childhood in gifted programs, O’Toole studied people the way others might study math. And then, she copied them—learning what most folks absorb naturally on the playground only through voracious novel reading and the aftermath of embarrassing gaffes.

I feel like this kind of thinking started when I was 13. Even as an adult, I studied other people to try to learn how they acted so I could figure out how to act.

Also, unlike in boys, the difference between typical and autistic development in girls may lie less in the nature of their interests than in its level of intensity. These girls may refuse to talk about anything else or take expected conversational turns. “The words used to describe women on the spectrum come down to the word ‘too,’” O’Toole says. “Too much, too intense, too sensitive, too this, too that.”

My parents also described me as “too sensitive” or “too naive” or “too much”.

She describes how both her sensory differences—she can be overwhelmed by crowds and is bothered by loud noise and certain textures—and her social awkwardness made her stand out. Her life was dominated by anxiety. Speaking broadly of people on the spectrum, O’Toole says, “There is really not a time when we’re not feeling some level of anxiety, generally stemming from either sensory or social issues.”

Story of my life, here.